Allergy and Immunology: Brief Literature Review on Oral Immunotherapy

The following is a list of recently published articles that are relevant to the topic of oral immunotherapy for allergies. This list is intended to accompany our article on this type of therapy for food allergies.

The articles have been selected by the MDalert.com editors based on the quality of the research, the importance of the finding, the number of people affected by it, and the cost of the therapy studied.

1. Ragweed-induced allergic rhinoconjunctivitis: current and emerging treatment options. Ihler F, Canis M. J Asthma Allergy. 2015 Feb 16;8:15-24. doi: 10.2147/JAA.S47789. eCollection 2015. Review. PMID: 25733916.
2. Safety and tolerability of 5-grass pollen tablet sublingual immunotherapy: pooled analysis and clinical review. Didier A, Bons B. Expert Opin Drug Saf. 2015 Mar 3:1-12. PMID: 25732009.
3. Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up. Caminiti L, Pajno GB, Crisafulli G, Chiera F, Collura M, Panasci G, Ruggeri P, Guglielmo F, Passalacqua G. J Allergy Clin Immunol Pract. 2015 Feb 25. pii: S2213-2198(15)00024-0. doi: 10.1016/j.jaip.2015.01.017. PMID: 2572594.
4. Impact of oral immunotherapy on quality of life in egg allergic children. Vazquez-Ortiz M, Alvaro M, Piquer M, Dominguez O, Giner M, Lozano J, Jiménez-Feijoo R, Plaza A. Pediatr Allergy Immunol. 2015 Feb 18. doi: 10.1111/pai.12355. PMID: 25692393.
5. Oral and sublingual immunotherapy for food allergy. Le UH, Burks AW. World Allergy Organ J. 2014 Dec 8;7(1):35. doi: 10.1186/1939-4551-7-35. eCollection 2014. Review. PMID: 25709745.
6. Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2014. Sicherer SH, Leung DY. J Allergy Clin Immunol. 2015 Feb;135(2):357-367. doi: 10.1016/j.jaci.2014.12.1906. Review. PMID: 25662305.
7. Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial. Burks AW, Wood RA, Jones SM, Sicherer SH, Fleischer DM, Scurlock AM, Vickery BP, Liu AH, Henning AK, Lindblad R, Dawson P, Plaut M, Sampson HA; for the Consortium of Food Allergy Research (CoFAR). J Allergy Clin Immunol. 2015 Feb 3. pii: S0091-6749(14)03745-2. doi: 10.1016/j.jaci.2014.12.1917. PMID: 25656999.
8. Study of induction of Tolerance to Oral Peanut: a randomised controlled trial of desensitisation using peanut oral immunotherapy in children (STOP II). Anagnostou K, Islam S, King Y, Foley L, Pasea L, Palmer C, Bond S, Ewan P, Clark A. Southampton (UK): NIHR Journals Library; 2014 Dec. PMID: 2564253.
9. Characterization of oral immune cells in birch pollen-allergic patients: impact of the Oral Allergy Syndrome and sublingual allergen immunotherapy on antigen presenting cells. Mascarell L, Rak S, Worm M, Melac M, Soulie S, Lescaille G, Lemoine F, Jospin F, Paul S, Caplier L, Hasséus B, Björhn C, Zeldin RK, Baron-Bodo V, Moingeon P. Allergy. 2015 Jan 29. doi: 10.1111/all.12576. PMID: 25631199.
10. Epinephrine Use in Positive Oral Food Challenges Performed as Screening Test for Food Allergy Therapy Trials. Noone S, Ross J, Sampson HA, Wang J. J Allergy Clin Immunol Pract. 2015 Jan 13. pii: S2213-2198(14)00462-0. doi: 10.1016/j.jaip.2014.10.008. PMID: 25609353.
11. Modified peanut oral immunotherapy protocol safely and effectively induces desensitization. Bird JA, Feldman M, Arneson A, Dougherty I, Brown LS, Burk CM, Kulis M, Burks W, Gill M. J Allergy Clin Immunol Pract. 2015 Jan 16. pii: S2213-2198(14)00576-5. doi: 10.1016/j.jaip.2014.11.020. [Epub ahead of print] No abstract available. PMID: 25609341.
12. Oral immunotherapy in cow's milk allergic patients: course and long-term outcome according to asthma status. Elizur A, Goldberg MR, Levy MB, Nachshon L, Katz Y. Ann Allergy Asthma Immunol. 2015 Mar;114(3):240-244.e1. doi: 10.1016/j.anai.2014.12.006. Epub 2015 Jan 14. PMID: 2559588.
13. Administration of a probiotic with peanut oral immunotherapy: A randomized trial. Tang ML, Ponsonby AL, Orsini F, Tey D, Robinson M, Su EL, Licciardi P, Burks W, Donath S. J Allergy Clin Immunol. 2015 Mar;135(3):737-744.e8. doi: 10.1016/j.jaci.2014.11.034. Epub 2015 Jan 13. PMID: 25592987.
14. Allergist-reported trends in the practice of food allergen oral immunotherapy. Greenhawt MJ, Vickery BP. J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):33-8. doi: 0.1016/j.jaip.2014.06.023. Epub 2014 Oct 29. PMID: 25577615.
15. Suppression of the immunologic response to peanut during immunotherapy is often transient. Gorelik M, Narisety SD, Guerrerio AL, Chichester KL, Keet CA, Bieneman AP, Hamilton RG, Wood RA, Schroeder JT, Frischmeyer-Guerrerio PA. J Allergy Clin Immunol. 2014 Dec 24. pii: S0091-6749(14)01646-7. doi: 10.1016/j.jaci.2014.11.010. PMID: 25542883.
16. A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy. Narisety SD, Frischmeyer-Guerrerio PA, Keet CA, Gorelik M, Schroeder J, Hamilton RG, Wood RA. J Allergy Clin Immunol. 2014 Dec 18. pii: S0091-6749(14)01600-5. doi: 10.1016/j.jaci.2014.11.005. PMID: 25528358.
17. Safety of sublingual immunotherapy Timothy grass tablet in subjects with allergic rhinitis with or without conjunctivitis and history of asthma. Maloney J, Durham S, Skoner D, Dahl R, Bufe A, Bernstein D, Murphy K, Waserman S, Berman G, White M, Kaur A, Nolte H. Allergy. 2015 Mar;70(3):302-9. doi: 10.1111/all.12560. Epub 2015 Jan 14. PMID: 25495666.
18. Current opinion and review on peanut oral immunotherapy. Deol S, Bird JA. Hum Vaccin Immunother. 2014;10(10):3017-21. doi: 10.4161/hv.32190. PMID: 25483680.
19. Sublingual immunotherapy in allergic rhinitis: efficacy, safety, adherence and guidelines. Aboshady OA, Elghanam KM. Clin Exp Otorhinolaryngol. 2014 Dec;7(4):241-9. doi: 10.3342/ceo.2014.7.4.241. Epub 2014 Nov 14. Review. PMID: 25436040.
20. Oral immunotherapy for the treatment of food allergy. Begin P, Chinthrajah RS, Nadeau KC. Hum Vaccin Immunother. 2014;10(8):2295-302. doi: 10.4161/hv.29233. PMID: 2542493.