Dermatology

Molecular Differences Between Pediatric and Adult Psoriasis Plaques

The pathology of pediatric psoriasis differs from that of adult psoriasis, a finding that has implications for treatment, researchers suggest.

Do you recognize this pustular rash in an elderly female?

An 80-year-old female with a history of arthritis and high blood pressure presents with recurrent lesions and erythema on the palms of her hands and the soles of her feet. On examination, hyperkeratosis, brown macules, and discrete pustules are seen on her palmoplantar surfaces. A fungal culture and serologic tests are unremarkable. Which of the following is most strongly associated with this patient’s condition?

A) Exposure to ultraviolet radiation
B) Prior HPV infection
C) History of cigarette smoking
D) Prior aspergillus exposure

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A Rare Reaction to a Popular Asian food

After visiting an Asian food festival, this 50-year-old male now presents with a pruritic, whiplash-striped, erythematous rash on his torso. Do you recognize the cause of this presentation?

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Uncommon Presentation or Rare Disease?

A young patient presents with a rough, irregular growth on his fourth finger. Is this lesion simply an unusual presentation of a common condition or is it indicative of a rare disease?

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Pedaling Purpura

This patient returned from a 4-hour bike ride with a non-blanching purpuric rash on his lower legs that spared the skin compressed by his socks. He had no significant medical history and denied taking medication. Was a bike ride the cause of this eruption?

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An Entire Family Presents with the Same Condition.

This patient has been diagnosed with a hereditary (consanguineous) form of palmoplantar keratoderma, a condition characterized by an overproduction of keratin in the palms and soles. The disorder varies in severity and can be complicated by frequent bacterial, viral, and fungal infections. Symptoms are generally managed with the use of emollients and keratolytic agents.

The condition appeared in the entire family due to consanguinity. Consanguinity among ethnic groups is not uncommon, leading to hereditary conditions commonly seen only in those population subsets.

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Pressure Ulcers Are Painful, Dangerous, Costly, and Preventable


  • Pressure ulcers are common throughout the world.
  • Many different types of pressure wounds and treatments exist.
  • The annual cost of pressure ulcers in the U.S. is about $11 billion.
  • Pressure ulcers are easily prevented.
  • Prevention is much less costly than treatment.

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