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November 20, 2017

NEJM Study Finds Osimertinib Exhibits 18.9 Months Progression-Free Survival vs. 10.2 Months With Standard Treatment for NSCLC Patients

By Mia Garchitorena
The NEJM published results from a phase III trial showing that osimertinib exhibited longer progression-free survival and could be a new first-line treatment for patients with untreated EGFR-mutated NSCLC.
NEJM Study Finds Osimertinib Exhibits 18.9 Months Progression-Free Survival vs. 10.2 Months With Standard Treatment for NSCLC Patients
November 9, 2017

FDA Warns Patients That Thermogram is No Alternative to Mammogram

By Mia Garchitorena

The U.S. Food and Drug Administration (FDA) has released a warning reminding patients that thermography should not replace mammography for breast cancer screening.

FDA Warns Patients That Thermogram is No Alternative to Mammogram
November 9, 2017

Adverse Events Caused 81% of Patients to Discontinue TKIs for CML, Study Finds

By Annette M. Boyle, MDalert.com Contributor
A new study found that adverse effects were the most common reason for patients with chronic myeloid leukemia to discontinue use of tyrosine kinase inhibitors.
Adverse Events Caused 81% of Patients to Discontinue TKIs for CML, Study Finds
November 9, 2017

New Combo Therapy Doubles Progression-Free Survival in Metastatic Breast Cancer Patients

By Annette M. Boyle, MDalert.com Contributor

A new study found that a combination of everolimus and fulvestrant doubled progression-free survival in these patients compared to fulvestrant alone.

New Combo Therapy Doubles Progression-Free Survival in Metastatic Breast Cancer Patients
November 9, 2017

Smartphone Data Accurately Predict Blood Glucose Levels

By Michael Vlessides, MDalert.com contributor

A new personalized prediction model uses smartphone-collected patient data and aggregate population data to create personalized blood glucose predictions for individuals.

Smartphone Data Accurately Predict Blood Glucose Levels
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Trending News

In cooperation with Reuters News and Reuters Health, we are proud to provide you with our continuously updated news feed. We select news that applies to physicians in all the major clinical specialties, as well as on finance, science, technology, and other areas.

Reuters Health Medical News

U.S. drinking water regulations tied to reduced arsenic exposure

By Lisa Rapaport (Reuters Health) – The public’s exposure to arsenic, a naturally occurring chemical element linked to cancer and birth defects, declined after U.S. regulators tightened restrictions Read More »

Brain damage from football concussions varies by position and career duration

By Lisa Rapaport (Reuters Health) - Football players may experience different degrees of brain damage after concussions depending on what position they play and how long they stick with the sport, a Read More »

Baby-gender 'reveal' parties may have a dark side

By Ronnie Cohen (Reuters Health) - Expectant parents are bringing back the surprise element of having a baby by learning the results of prenatal ultrasound reports in ever more elaborate " Read More »

Stressed out parents less likely to cook homemade meals

By Lisa Rapaport (Reuters Health) - On days when parents feel stressed or depressed, kids are less likely to get homemade food for dinner, a U.S. study suggests. Beyond just serving up more fast Read More »

Drug resistance-associated substitutions identified in HCV genes

By Marilynn Larkin NEW YORK (Reuters Health) – In patients who fail direct-acting antiviral therapy for hepatitis C virus (HCV) infection, resistance-associated substitutions (RASs) vary by HCV Read More »

New therapeutic target for ER-positive breast cancer shows promise

By Marilynn Larkin NEW YORK (Reuters Health) – Protein tyrosine kinase 6 (PTK6) inhibition might one day be an effective treatment for ER+ breast cancers, given the enzyme’s role as a promoter of Read More »

Diabetics with related eye damage have increased falling risk

By Lisa Rapaport (Reuters Health) - People with diabetic retinopathy are more likely to fall than diabetics who have not developed vision problems, a study in Singapore suggests. Among almost 9,500 Read More »

Higher eosinophil counts in sputum may help predict COPD exacerbations

By Marilynn Larkin NEW YORK (Reuters Health) - High eosinophil concentrations in sputum are a better biomarker than blood concentrations for identifying patients with chronic obstructive pulmonary Read More »

See all news »

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figure1

Image of the Week

Back Pain

Back Pain

A 30-year-old male presents with a one-year history of worsening lower back pain and alternating buttock pain. He mentions his symptoms are typically worse first thing in the morning, but seem to remit later in the day with NSAIDs and exercise. Physical examination reveals swelling of the proximal interphalangeal joints of several digits, restricted lumbar movement, and tenderness of the sacroiliac joint. An X-ray demonstrates the findings seen here. Which of the following extra-articular clinical manifestations is most commonly associated with this patient’s condition?

A) Blurred vision
B) Right lower quadrant pain
C) Plaques with silver scale
D) Shortness of breath

Click here for answers to this clinical conundrum

Visit Figure 1 for more medical images and information.

Clinical Trials

Use our ClinicalTrials.gov feed to find trials in which your patients could enroll. In some cases, experimental drugs are a patient’s only hope. This section will regularly report on trials in the most common disease states, as they are getting underway.